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KMID : 0352819880040010053
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Kosin Medical Journal
1988 Volume.4 No. 1 p.53 ~ p.60
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Effects of Estradiol-17B on cAMP Phosphodiesterase of Rat Liver
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Abstract
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cAMP phosphodiesterase is known as an enzyme which regulates intracelluar cAMP concentration. This study was performed to know how estrogen has an effects on the cAMP phosphodiesterase of the rat liver.
The results are the followings.
1. cAMP phosphodiesterase activity increased about 2 times in estrogen-treated group than in control group.
2. In control roup, the portal area show higher activity than other areas.
3. Endothelial cells and Kupffer´s cells show higher activity than hepatocytes in both estrogen-treated and control groups. Between two group, found was not differences of cAMP phosphodiesterase activities of two cell types.
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KEYWORD
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